Seller Name: DAVID W
Intracellular Delivery: Fundamentals and Applications (Hardcover)

Healthcare, Lab & Life Science

Wytheville, VA 24382



ITEM#: 13431012

This book features a special subsection of Nanomedicine, an application of nanotech­nology to achieve breakthroughs in healthcare. It exploits the improved and often novel physical, chemical and biological properties of materials only existent at the nanometer scale. As a consequence of small scale, nanosystems in most cases are efficiently uptaken by cells and appear to act at the intracellular level. Nanotechnology has the potential to improve diagnosis, treatment and follow-up of diseases, and includes targeted drug delivery and regenerative medicine; it creates new tools and methods that impact sig­nificantly upon existing conservative practices.

This volume is a collection of authoritative reviews. In the introductory section we define the field (intracellular delivery). Then, the fundamental routes of nanode­livery devices, cellular uptake, types of delivery devices, particularly in terms of localized cellular delivery, both for small drug molecules, macromolecular drugs and genes; at the academic and applied levels, are covered. The following section is dedicated to enhancing delivery via special targeting motifs followed by the introduction of different types of intracellular nanodelivery devices (e.g. a brief description of their chemistry) and ways of producing these different devices. Finally, we put special emphasis on particular disease states and on other biomedical applications, whilst diagnostic and sensing issues are also included.

Intracellular delivery / therapy is a highly topical which will stir great inter­est. Intracellular delivery enables much more efficient drug delivery since the impact (on different organelles and sites) is intracellular as the drug is not supplied externally within the blood stream. There is great potential for targeted delivery with improved localized delivery and efficacy.


ISBN 9789400712478
Genre SCIENCE / Life Sciences / Molecular Biology
Format Hardcover
Pages 867
Publisher Date 2011-06-28 00:00:00.0
Publisher Springer Verlag
Copyright Year 2011
Thickness 2.0 in
Unit weight 3.05 lb
Height 9.25 in
Wdth 6.25 in
Language English
Subtitle Fundamentals and Applications
Series Name Fundamental Biomedical Technologies
Series Volume Number 5
Audience College/higher education
Country of Origin United States
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